In this conversation, Daniel Belkin and Mitch Belkin speak with Joel Topf, MD, about contrast-associated nephropathy. We discuss Acute Kidney Injury (AKI), the value of creatinine as a marker for AKI, how to evaluate volume status, the evidence around contrast-induced/contrast-associated nephropathy, recommendations on fluids to prevent AKI in patients with Chronic Kidney Disease, and comparing venous and arterial contrast with respect to the risk of AKI.
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Who is Joel Topf?
Dr. Topf is a clinical nephrologist in Detroit, who is a partner and medical director at St Clair Nephrology and an assistant professor at Oakland University William Beaumont School of Medicine. He is the co-creator of NephMadness and NephJC. He hosts multiple podcasts, blogs at pbfluids.com, and tweets @Kidney_boy.
References:
- Joel Topf’s Blog
- Twitter: @Kidney_Boy
- Joel Topf – Grand Rounds Presentation on Contrast Nephropathy
- The PRESERVE trial
- N-Acetylcysteine and Contrast-Induced Nephropathy in Primary Angioplasty
- Prevention of Contrast-Induced Nephropathy With Sodium Bicarbonate
- Craig Brater 1998 – NEJM review on Diuretics
- Chlorthalidone for Hypertension in Advanced Chronic Kidney Disease
- Effect of Salt Substitution on Cardiovascular Events and Death