Tag: Immunology

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33. Ross Levine, MD, PhD: Deep Dive on Acute Myeloid Leukemia

Ross Levine

In this conversation, Daniel Belkin and Mitch Belkin interview Ross Levine, MD, PhD about Acute Myeloid Leukemia and its treatment. They discuss the different types of leukemias, the history of AML treatment, including chemotherapy and stem cell transplantation. They touch on Graft vs Host Disease, treatment after relapse, and open questions in leukemia, including future trials, and further investigation of ven/aza (Azacitidine/venetoclax).

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Who is Ross Levine?

Dr. Ross Levine of the Memorial Sloan Kettering Cancer Center. Dr. Levine studies hematologic malignancies and is a world-renowned expert on myeloproliferative neoplasms and acute myeloid leukemia. 

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32. Adam J Brown, MD: History of Rheumatology, The Black Death, and Why You Shouldn’t Inject Uric Acid Crystals into Your Knee

Adam J Brown

In this conversation, Daniel Belkin and Mitch Belkin interview Adam J Brown, MD about the field of Rheumatology, autoimmune diseases, and his podcast Rheuminations. They discuss the history of gout, plaquenil, the relationship between infectious diseases and rheumatologic conditions, the inflammasome, autoinflammatory disorders, vasculitis, fibromyalgia, Covid, and much more.

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Who is Adam J Brown?

Dr. Adam J. Brown is a Rheumatologist at the Cleveland Clinic. Dr. Brown is the author of the book Rheumatology Made Ridiculously Simple. He is also the host of the Healio podcast Rheuminations, which focuses on autoimmunity, rare diseases, and the history of medicine. 

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Podcast

30. Polly Matzinger, PhD: Dangerous Ideas in Immunology

Polly Matzinger

In this conversation, Daniel Belkin and Mitch Belkin interview Polly Matzinger, PhD, about her model of immunology, which she calls ‘The Danger Model’. They discuss how The Danger Model helps explain aspects of immunology ignored by the self/non-self model, including why mothers don’t reject their fetuses, autoimmune diseases, organ transplant rejection, cancer surveillance, allergy and more.

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Who is Polly Matzinger?

Polly Matzinger received her PhD in Biology from UCSD before completing a postdoc at Cambridge. She then worked at the Basel Institute for Immunology before moving to the NIH, where she was a section head at the National Institute of Allergy and Infectious Diseases of the so-called “Ghost Lab”. She is the creator of the Danger Model (1994), which argues the immune system discriminates between dangerous and safe by recognition of pathogens or alarm signals from injured or stressed cells and tissues. 

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